Vincristine Sulphate Injection
Product/Composition:- | Vincristine Sulphate Injection |
---|---|
Strength:- | 1mg/ml |
Form:- | Injection |
Production Capacity | 1 Million Injection/Month |
Therapeutic use:- | Anti Cancer |
Package Insert/Leaflet: | Available upon request |
About Vincristine Sulphate Injection
Vincristine Sulphate Injection is a chemotherapy drug used to treat various cancers. It is in a group of drugs known as vinca alkaloids.
In 1963, the FDA approved Vincristine Sulphate Injection. It is now a key drug for treating pediatric and adult cancers.
Research on other targeted therapies is also ongoing. The goal is to improve their efficacy and reduce toxicity.
Uses of Vincristine Sulphate Injection
Vincristine Sulphate Injection is also found to be useful for the treatment of certain other types of cancers, including-
Leukemia, Lymphomas, Neuroblastoma, Wilms’ tumour, small cell lung cancer.
The drug is used in combination with another chemotherapy drug with maximum efficacy.
How Does Vincristine Sulphate Injection Works?
The use of Vincristine Sulphate has been made available across different hospitals by specialists.
It works easily, and this begins with the interference with the cancer cell division process by binding to the tubulin, which is the protein that helps from microtubules.
This, in turn, disrupts the entire mitotic spindle and halts the division of the cells, eventually leading to death.
How do I take Vincristine Sulphate Injection?
The intake of Vincristine Sulphate Injection is being done under the complete supervision of a specialist. The consumption is done by intravenous (IV) injection.
The dose is based on the type of cancer, the patient’s weight, and their general health.
Moreover, regular testing and even medical evaluations are also required to monitor the progress and even side effects.
By following all of the required steps, the intake of Vincristine Sulphate Injection can be done easily.
When is Vincristine Sulphate Injection not suitable?
Different individuals have to be taken care of at the time of using Vincristine Sulphate Injection.
Patients with any of the pre-existing condition nerve conditions or other severe liver disease.
If you are pregnant and also breastfeeding, then it is advisable to seek doctor’s help.
Individuals with hypersensitivity or intake of other drugs then do not take Vincristine Sulphate without a consultation with a doctor.
Side Effect
INTERACTIONS
Vincristine can interact with other medicines, including phenytoin, digoxin, antifungals, and some antibiotics.
In another case, live vaccines should be avoided as vincristine suppresses the immune system.
What should I discuss with my healthcare provider before using Vincristine Sulphate Injection?
Patients who are undergoing any pre-existing conditions like nerve disorders or also associated with liver should consult first with the doctor.
When you are consuming any other medicines or supplements,
If you are undergoing or developing any allergies to chemotherapy drugs.
Women who are planning to become mothers also need careful consideration.
Missed Does
Vincristine should only be taken carefully and under the close watch of a doctor. If you have forgotten to take the dose, then it is advisable to consult with a doctor.
Over Does
Overdosing can cause many side effects. These include nerve damage, gastro problems, and trouble breathing.
What should I avoid while taking Vincristine Sulphate?
There is a need to avoid exposure to infections, and this is due to reduced immunity.
Try to minimize the contact with sick people.
Also, there is a need to avoid consuming alcohol to reduce further strain.
What Other drugs will affect Vincristine Sulphate?
Drugs like ketoconazole that can inhibit the liver enzyme can increase the toxicity level and hence need avoidance.
In the case of other chemotherapy agents, the side effects can be increased.
What Special Dietary Instructions Should I follow?
Individuals must consume a rich and balanced diet to maintain strength and immunity. It is also advisable to drink lots of water to stay hydrated and keep toxin elements away. Further, patients need to avoid grapefruit juice as it can interact with other medicines as well.
Warning & Precautions
Patients connected with the intake of vitamin Sulphate should regularly perform blood tests as it is necessary to monitor the white blood cells and liver functionality.
If you experience any symptoms of nerve damage, then be sure to report it to the doctor on an immediate basis.
Avoiding Vincristine Sulphate during pregnancy is recommended as it can harm.
Where can I Get More Information?
Consulting with an oncologist or pharmacist would help you to give proper information and begin with the treatment.
There is also a need to refer to the patient info leaflet provided with the injection.
This way, the right way to use it and other details can be taken into account.
Deciding on treatment
-Advantages
The use of Vincristine Sulphate is in context with certain cancers.
Often utilized in combination therapy for the betterment of the results.
It is also administered by professionals, and this ensures better delivery.
-Disadvantages
There are risk of potential side-effects and majorly includes damage in the nerves.
It requires careful monitoring, and even patients need to visit the hospital.
Remember, Vincristine Sulphate is also not suitable for all patients and hence needs careful consideration.