Sorafenib Tablets
| Product/Composition:- | Sorafenib Tablets |
|---|---|
| Strength:- | 200mg |
| Form:- | Tablets |
| Production Capacity | 10 Million Tablet/Month |
| Packaging:- | 120 Tablets / Bottle, 30 Tablets / Bottle |
| Therapeutic use:- | Anti Cancer |
| Package Insert/Leaflet: | Available upon request |
What is Sorafenib?
Sorafenib tablet belongs to the tyrosine kinase inhibitor and is mainly the oral anticancer medication for individuals to be treated.
As we all know the fact that cancer is spreading at a rapid pace among individuals, and its control on time is needed with best-suited medicine.
Therefore, Sorafenib helps individuals by blocking the signal that cancer cells use to grow and, in turn, spread. People suffering from liver cancer, kidney cancer, or thyroid cancer are suggested to begin their treatment with Sorefenib.
Different uses of Sorafenib
The use of Sorafenib is mainly suggested for the advanced treatment of liver cancer, slowing the growth of cells and cutting off the blood supply that tumors need to grow.
Most people come across kidney cancer, and Sorafenib helps stop cancer cell multiplication and, in turn, decreases tumor development with the targeted action.
When thyroid cancer does not respond to radioactive iodine, Sorafenib blocks tumor development and helps regulate the disease.
Indications
Sorafenib can also interact with other drugs, and they can mainly affect the liver enzyme. The different medicines are- Rifampin, Phenytoin, Carbamazepine, and Warfarin, and it can be even CYP3A4 inhibitors like Ketoconazole.
Drug Interactions
Sorafenib can also interact with other drugs, and they can mainly affect the liver enzyme. The different drugs are Rifampin, Phenytoin, Carbamazepine, and Warfarin, and they can even be CYP3A4 inhibitors like Ketoconazole.
Can Take With Other Medicines:
Sorafenib Tablets can be combined with anti-nausea medications.
Individuals can also use it along with some painkillers, but it has to be under the complete supervision of an expert.
Moreover, sometimes Sorafenib Tablets are also used along with targeted therapies.
Medications to Avoid:
The consumption of Strong CYP3A4 inducers/inhibitors has to be avoided during Sorafenib intake.
The risk of bleeding and NSAIDs has to be avoided, and hence consideration is needed.
The use of Blood thinners is also not advisable.
Benefits
Sorafenib tablets can easily slow down tumor growth and progression, and in this manner, individuals can help themselves to withstand strong during treatment.
In advanced cancer, Sorafenib can also improve the survival rate.
Do offer an oral non-invasive treatment option.
Considered to be suitable in cases when surgery or radiation is not possible.
How Does It Work?
Sorafenib usually works by blocking the multiple protein kinases that are involved in the growth of tumors and angiogenesis- which means the formation of new blood vessels that feed tumors.
This way, the medicine helps to prevent cancer cells from increasing and dispersion.
Dosage Guidelines
The standard dose that adults can take is 400 mg twice daily.
It has to be consumed 1-2 hours before the meal.
Furthermore, the dosage has to be adjusted depending on one’s condition and seeking the best medical health expert advice.
Direction for Use/How to Use:
The Sorafenib tablets have to be swallowed only with water and do not adopt crushing or chewing.
Consistency is also required as it can help maintain/balance the condition.
The instructions that come along with the Sorafenib tablet have to be followed for betterment.
When Not to Use:
Women need extra care as during pregnancy has to be avoided its consumption.
If you are undergoing severe to mild liver impairment.
Known to develop allergies upon taking Sorafenib tablets.
Please do not take it in combination with other drugs.
Top safety measures to be followed
People should considering using an active contraception during and after treatment.
Individuals must not forget to monitor their blood pressure level and along with liver functioning.
Do not considering taking grapefruit juice, which affects drug metabolism.
Your body requires a sufficient amount of water and has to manage the same.
Worries
Individuals should monitor and report in case of Hand-foot skin reaction, diarrhea, fatigue, or hypertension.
There can be the possibility of bleeding when you combine it with blood thinners, and hence care is needed.
It can also interfere with/affect thyroid or heart function.
Does require frequent monitoring.
Precautions or Warnings
Young children less than eighteen should not be given.
Patients with either heart-related problems or liver has to take utmost care.
If you have a planned surgery or dental procedure, you must inform your doctor beforehand.
It can also develop harm to the developing fetus and, hence, avoid it if pregnant or planning pregnancy.
How can I help to solve my condition in another way?
Patients should not neglect to consume a rich diet and should remain active and well-tolerated against treatment.
It is advisable to quiet down smoking and alcohol consumption.
Communicate openly with your care team about side effects
Some necessary lifestyle commendations
You need to eat small meals with rich food involved.
You must avoid consuming spicy or greasy food.
Fluids are required in your body, so try to keep your body hydrated.
Make use of gentle skincare for hand-foot reactions.
Try to limit your exposure to the sun and use sunscreen.
Comparison with Other Treatments
When Sorafenib tablets are used, compared to chemotherapy, Sorafenib is less toxic and is more oral.
In another case, when compared with other TKIs, it has a broad range of targets.
It may be less effective if in case cancer is highly aggressive, but it is often first-line in inoperable cases.
Considering the advanced treatment- of liver cancer, this can be done along with Lenvatinib or Regorafenib.
What Not to Do
Do not try to skip your dose or overdose, as it can be risky. Hence, it is advisable to maintain your dosage intake on a daily basis, as needed.
You need to avoid self-medication or stopping abruptly.
Make sure to talk to your concerned doctor if you are looking to combine it with some herbal supplements.
Must avoid alcohol, smoking, and NSAIDs.
Storage Instructions
The storage of Sorafenib Tablets is advised to be at room temperature and must be away from moisture, heat, and direct sunlight.
If you have pets and children at your home, you need to be double attentive as need to keep out of reach of them.
Do check the expiry date before consumption.