Invert Sugar 5% injection
Product/Composition:- | Invert Sugar 5% injection |
---|---|
Strength:- | 250ml / 500ml / 1000ml |
Form:- | Injection |
Production Capacity | 1 Million Injection/Month |
Therapeutic use:- | Fluid Therapy |
Package Insert/Leaflet: | Available upon request |
What is Invert Sugar 5% Injection?
Invert Sugar 5% Injection in a sterile IV solution. It contains an equal mix of fructose and glucose. It offers a quick and balanced energy source for parenteral nutrition and urgent metabolic needs.
Isotonic solutions are often used in hospitals for critically ill patients. This is particularly true for people in intensive care units (ICUs) or undergoing major surgery.
It is also typically added to Total Parenteral Nutrition (TPN) therapy, where oral or enteral feeding is not feasible.
Uses of Invert Sugar 5% Injection
This injection is a valuable source of carbohydrates in various clinical conditions. It mainly supports energy metabolism for patients with trauma, burns, or infections.
It also helps those with high caloric needs who can’t get enough nutrition by mouth. It keeps glucose steady when blood sugar is low. It also reduces protein breakdown and helps liver glycogen.
Uses
Glucose provides rapid energy; fructose offers sustained release via hepatic metabolism. Beneficial in the management of hypoglycemia in critically ill patients.
Facilitates recovery of tissues caused by trauma or surgery. A required component of TPN in non-oral-fed patients. Facilitates re-establishment of metabolic balance in acute illness.
Indications
Invert Sugar 5% Injection is indicated for:
Parenteral carbohydrate replacement in patients who require it. Management of catabolic state patients such as sepsis or burns.
Surgical patients with increased energy expenditure. ICU patients who are unable to maintain oral nutrition. Individuals with severe gastrointestinal conditions preventing digestion.
Can Take With Other Medications
Invert Sugar 5% Injection is generally compatible with many drugs on intravenous administration. It is usually given in TPN mixes with amino acids, lipids, electrolytes, and vitamins.
Be careful not to mix with agents that can cause reactions or drugs that react with glucose or fructose.
Talk to a doctor or nurse before mixing IV drugs at all times. This helps ensure chemical compatibility and prevents unwanted side effects.
Medications to Avoid
There are some medications that should be shunned with Invert Sugar 5% Injection to avoid interaction or incompatibility. These include:
Benefits
Invert Sugar 5% Injection has several clinical benefits:
Side Effects
Generally safe under medical supervision, but the following side effects can occur:
How Does It Work?
Invert Sugar 5% Injection works by delivering glucose and fructose into the bloodstream. Glucose gives quick energy, while fructose is broken down slowly in the liver.
This makes a steady flow of energy happen. Its dual action provides a balanced blood glucose level and supports metabolic requirements. Pure glucose infusions, however, can rapidly increase blood sugar.
Dosage Guidelines
Adjust the Invert Sugar 5% Injection dose according to the patient’s nutrition needs, age, weight, and health. Usually:
Direction for Use
Give this injection through an IV. You can use either peripheral or central venous access based on the total osmolarity. It should be administered under the guidance of a competent healthcare expert.
Deliver through an infusion pump to regulate the rate of delivery. Filter the solution prior to administration to assure clarity and particle freedom.
Do not give this with blood components or medications unless you confirm compatibility.
How to Use
Verify the solution for container integrity and clarity. Administer by a sterile IV device.
Inject slowly and monitor for any side effects. Do not mix with incompatible solutions or medications.
Stop right away if you notice any signs or symptoms of infection or inflammation at the injection site.
When Not to Use
Invert Sugar 5% Injection is not to be used in the following:
Hypersensitivity to glucose or fructose. Diabetic ketoacidosis without concurrent insulin therapy.
Severe hepatic failure or fructose intolerance. Hyperosmolar coma or unmanageable hyperglycemia.
Established hereditary fructose intolerance or glucose-galactose malabsorption patients.
Safety Advice
Use only under close medical supervision in a hospital setting. Continuous blood sugar and renal function monitoring.
Adjust dose in renal or hepatic impairment. Implement an aseptic technique to avoid infection.
Use infusion pumps to avoid fluid overload or too rapid error.
Concerns
The issues include risks of hyperglycemia for diabetic patients, defects in fructose metabolism if the liver is impaired, and possible drug interactions.
High volumes should be closely monitored to avoid fluid overload. This is especially important for patients with weak heart or kidney function.
Precautions
Avoid in those with hereditary fructose intolerance. Caution in renal dysfunction or hepatic dysfunction.
Repeated monitoring of electrolytes, glucose, and fluid balance. Prevent extravasation; administer long-term infusion via a central line. Employ an alternative source of carbohydrates for unstable diabetics.
Warnings
Avoid using it if the solution is murky or the container is broken.
Not for self-administration. Use with caution in children and elderly.
Always check the expiry date and storage conditions. Infuse slowly to prevent metabolic imbalance.
What Else Can I Do to Help My Condition?
In addition to IV carbohydrate replacement, overall nutritional adequacy is crucial. Consider:
Well-balanced amino acid and lipid supplementation if on TP. Attentive fluid and electrolyte management.
Gentle exercise or physiotherapy (if possible) to avert muscle atrophy. Working with a dietitian for long-term diet planning upon discharge.
Treatment of underlying medical issues to reduce potential future hospitalizations.
Special Dietary & Lifestyle Recommendations
Patients treated with Invert Sugar 5% Injection should:
Avoid undue oral sugar intake unless otherwise directed. Stress well-balanced, protein-enriched meals upon return of oral feeding.
Be free of processed food post-recuperation and stay hydrated. Regular follow-up with a dietitian. Monitoring of blood glucose if diabetic or insulin-resistant
Comparison with Other Treatments
Invert Sugar 5% provides a steady energy release from both glucose and fructose. This makes it ideal for critical care, where maintaining balance is crucial.
Dextrose 5% quickly raises glucose levels. It is mainly used for hydration and when energy needs are low.
Fructose IV is processed in the liver. It can help boost liver metabolism in certain cases. However, its use is limited because it doesn’t rely on linlin and can cause lactic acidosis.
What Not to Do
Do not self-inject. Do not use expired or damaged solution. Do not take more than the recommended dose.
Do not use with incompatible medications. Do not fail to monitor regularly when on long-term infusion
Storage Instructions
Store below 25°C in dry place
Keep it away from the light and heat
Do not try to freeze this solution
Keep away from it from small children
Use only when the solution is clear and particles are not present