What is Dextran 40 with Sodium Chloride?

Dextran 40 with Sodium Chloride is key to the recovery process.

It’s used to replace body fluids that are lost because of heavy bleeding or a serious injury.

Giving this treatment through an IV increases blood volume and also helps circulation.

Product Overview

Dextran 40 with Sodium Chloride is a clear fluid that’s injected to treat low blood volume.

It’s a combination of Dextran 40, which is a sugar-like substance, and Sodium Chloride, commonly known as salt.

When you use them together, they help your body recover from trauma, surgery, or major fluid loss.

Description

Dextran 40 is a sugar solution made of small, branching chains. Certain bacteria create it, and it helps keep fluid in your blood vessels.

If you mix it with saline, it becomes a sterile liquid that’s safe for emergency IV use.

Indications & Uses

Dextran 40 helps people who go into shock from things like big blood loss, bad burns, or surgery.

It can also be used during surgeries that need a heart-lung machine.

It helps prevent blood clots after some surgeries, like hip operations.

Benefits

Dextran gives your body a refreshing boost after an injury.

To feel stronger and more energized, replace the fluids and salts your body needs.

It adds back the fluids your body has lost. This keeps you in balance and helps you work well.

This prevents dehydration from setting in.

Dextran helps support brain function and gets your body’s systems back on track after a serious injury.

It helps with recovery by putting back salts and water that the body needs, making it happen faster.

Side Effects

Dextran 40 Injection with Sodium Chloride may cause side effects, although these can be common or serious.

Mechanism of Action

Dextran works by increasing blood volume and improving blood flow.

Dextran 40 pulls fluid into blood vessels and helps prevent cells from sticking.

This action makes circulation smoother. 

How to Use

To use dextran 40 safely, first open the outer wrap. Then, carefully pull out the solution bag.

Next, attach the administration set by twisting the pin into the bag’s port.

Get the bag in position and make sure it’s secure.

Now, hang it up and squeeze out any air from the drip chamber. Release the clamp to start the flow.

Next, connect the setup to the vein. Adjust the flow rate as needed.

It’s important to follow dose limits. Also, check for any particles in the solution before using it.

When Not to Use

Dextran 40 isn’t the top choice for every patient. Using it can be unsafe or risky in certain circumstances.

Avoid this if you had an allergic reaction to Dextran before.

Do not use Dextran 40 Injection with Sodium Chloride if you have kidney problems or kidney failure.

Stop if you start having breathing or heart problems.

Don’t exceed the recommended amount.

Be careful if you have had bleeding or surgery.

Warnings & Precautions

Dextran can be risky, so it’s best to take some precautions first.

Dextran may impair blood clotting and prolong bleeding time.. It’s especially crucial after surgery or an injury when patients need close monitoring.

If you have kidney problems, taking dextran might make them worse. Use it carefully, especially if your kidneys aren’t working well.

Dextran may change your test results in unexpected ways. To be on the safe side, get a blood test before the infusion starts.

Dextran 40 Injection with Sodium Chloride should only be used by pregnant or breastfeeding women if they need it.

Dextran use can trigger severe reactions that are uncommon but potentially serious. Reactions can occur right away, within minutes of the infusion starting.

You can have severe allergic reactions at any time when using Dextran 40 Injection with Sodium Chloride.

A test dose of 20 mL of dextran can help reduce the risk of serious allergic reactions, but there is still a risk.

As soon as a reaction occurs, stop the infusion. Ensure emergency assistance is available during treatment.

Using too much dextran can put a strain on the heart or lungs. 

Drug Interactions

Dextran 40 in Sodium Chloride may not work well with some other medicines, foods, or health issues.

Dextran 40 in Sodium Chloride raises the risk of bleeding. When you use blood thinners like warfarin, heparin, or aspirin, the risk goes up.

Therefore, it’s important to be careful and have close supervision.

Corticosteroids can cause fluid issues, so patients need close monitoring.

This solution has sodium, which can be risky for people with heart failure or kidney issues.

When sodium levels get too high, it can cause fluid buildup in the body. This leads to swelling and other issues. 

Diet & Lifestyle Advice

When you’re on Dextran 40 Injection with Sodium Chloride treatment, your doctor may advise you to drink more fluids.

To feel your best, focus on three main things: a balanced diet, staying hydrated, and getting plenty of rest.

Storage

Store Dextran 40 Injection with Sodium Chloride at room temperature, around 20 to 25°C (68 to 77°F).

Choose a dry spot to keep it, and steer clear of anything too chilly or icy.

Just make sure it’s safe and not exposed to extreme temperatures.

FAQs

In some cases, Dextran 40 can have an effect on the kidneys. You’re more at risk for this if kidney issues are already a problem or you’re taking a high dose.

A test dose is often needed just to be safe. It helps detect any allergic reactions to Dextran 40 before giving the full amount.

No, Dextran 40 can’t take the place of blood entirely. It does help with blood flow, but it doesn’t get the job done like real blood does, like carrying oxygen