Cisplatin Injection
| Strength:- | Cisplatin Injection |
|---|---|
| Product/Composition:- | 50mg/50ml |
| Form:- | Injection |
| Production Capacity | 1 Million Injection/Month |
| Therapeutic use:- | Anti Cancer |
| Package Insert/Leaflet: | Available upon request |
What Is Cisplatin Injection?
Treating many kinds of cancer, including testicular, ovarian, bladder, lung, head and neck tumors, cisplatin injection is a method of chemotherapy.
It functions by causing harm to cancer cells’ DNA, which ultimately results in their demise. Its active ingredient, Cisplatin, harms the cancerous cell’s DNA, inhibiting its growth and reproduction.Â
Usually, doctors give this drug through an IV drip while the patient is in a clinic or hospital setting. Cisplatin is normally used during a cycle of treatment with several other chemotherapy medications.Â
Cisplatin is an effective cancer treatment, but it can have some significant adverse effects. These side effects can include kidney damage, loss of hearing, nausea, vomiting, and issues with nerves.
Because of this, patients undergoing treatment are monitored with regular checkups to evaluate kidney function, hearing capability, and blood counts.
People with pre-existing diseases of the kidneys or issues with hearing should avoid using this drug unless advised by a physician.
Even though Cisplatin has side effects, it is still an important part of cancer treatment.
How Is Cisplatin Given?
Cisplatin is administered through a slow and controlled intravenous infusion, usually in a hospital setting or outpatient clinic.
Your individual dose is calculated based on your specific cancer diagnosis, your body surface area, and the overall tolerance level to the drug.
Usually administered every three to four weeks, this medication is frequently used in conjunction with other chemotherapy treatments. Â
To minimize kidney injury, ample fluids will be provided to you before and after the infusion to help wash out the medication from the system.
Other doctors may provide measures to control nausea and other antiemetics to prevent post-procedure discomfort.
Each session may take several hours during which constant attention is given to watch and manage any possible side effects. Â
How Does Cisplatin Work?
Cisplatin attaches to the DNA in the cancerous cells and alters its configuration. This interferes with the cell’s proliferation and reproduction ability.
Hence, it kills the cell. The higher rate of instability within cancer cells in comparison to normal cells means cancer cells are much more vulnerable to this mechanism of action. Â
Unfortunately, these drugs have the disadvantage of not distinguishing cancerous cells from non-cancerous ones, which is why patients suffer from side effects such as kidney injury, vomiting, and even permanent deafness.
In an attempt to lessen these side effects, responsive care like providing fluids, antiemetics, and close evaluation is incorporated.
Other Uses of Cisplatin
Besides its primary function in handling testicular, bladder, and ovarian cancers, Cisplatin is also useful for lung, cervical, head, neck, and esophageal cancers.
Even mesothelioma and certain malignant brain tumours are treated using it. Â
Often, Cisplatin is part of broader treatment plans that incorporate radiation or immunotherapy to maximize results and mitigate side effects.
Nanoparticles and plant-derived compounds are being studied for enhanced targeting and reduced toxicity, sparking exciting new research. Â
Side Effects of Cisplatin
Typical adverse effects consist of:
Serious adverse effects could consist of:
Precautions Before Taking Cisplatin
Before starting treatment, be sure to:
Inform your doctor of any hearing issues, allergies, or kidney-related conditions. Provide a complete list of all the drugs, vitamins, and herbal therapies you now take.
Avoid pregnancy during and after treatment, as Cisplatin can harm unborn babies. If you or your spouse are capable of getting pregnant, use an effective birth control method.
Stay hydrated before and after each infusion to protect your kidneys. Avoid vaccines without medical approval, as your immune system may be weakened.
If you experience numbness in your limbs, decreased urine, or changes in your hearing, notify your doctor right once.
Throughout treatment, routine blood tests and evaluations of kidney function are crucial.
Diet & Lifestyle Tips During Treatment
To support your body during treatment:
What to Do in Case of Overdose
In the event that you suspect an overdose, get emergency care right away. Cisplatin overdose can result in severe kidney damage, hearing loss, and low counts of blood cells.
Do not try to manage an overdose situation at home. Hospitalized patients may need IV fluids, medication, and continuous monitoring.
It is imperative that you take your medications as directed. Never alter the dosage without consulting your doctor. Â
Additional Information You Should Know
Cisplatin requires a prescription, but only skilled medical experts should administer it. Cisplatin should never be stored at home or attempted to be self-injected.
Discuss with a clinician if you are planning to conceive, as it might impact your fertility.
Keep a look out for any unforeseen consequences, such as hearing loss or nerve injury. If you feel symptoms, get in touch with a professional.
Storage Instructions
Cisplatin must be stored and handled by healthcare staff. If short-term storage is needed, it should be kept in a refrigerator at 2°C to 8°C (36°F to 46°F), away from sunlight and freezing conditions. Ensure that children