albendazole
  1. albendazole
  2. Albendazoletablet
  3. Albendazole 1
  4. Albendazole 2

Albendazole Tablets

Product/Composition:- Albendazole Tablets
Strength:- 300mg,400mg
Form:- Tablets
Production Capacity:- 10 Million Tablet/Month
Packaging:- 10 X 10 Tablets / Box, 10 X 5 Tablets / Box
Therapeutic use:- GIT Agent
Package Insert/Leaflet:- Available upon request
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We are a 100% export-oriented company and do not engage in domestic sales within India.

Understanding Albendazole Tablets

Albendazole is a broad medicine utilized to treat many types of parasitic worm infections. This medicine is a benzimidazole. It works by blocking tubulin polymerization. This leads to fewer microtubules in the parasites’ intestinal cells. This impairs their metabolism and results in their eventual demise. Albendazole is extensively prescribed in both human and veterinary medicinal requirements.

Uses of Albendazole Tablets

Albendazole is used for the treatment of numerous parasitic infections, including:

  • Neurocysticercosis – caused by Taenia solium or pork tapeworm

  • Hydatid disease – caused by Echinococcus granulosus

  • Hookworm infections – Ancylostoma duodenale, Necator americanus

  • Ascariasis – roundworm infection caused by Ascaris lumbricoides

  • Trichuriasis – whipworm infection caused by Trichuris trichiura

  • Enterobiasis – pinworm infection caused by Enterobius vermicularis

  • Strongyloidiasis – caused by Strongyloides stercoralis

  • Giardiasis – in children for Giardia lamblia infections

  • Filariasis – as part of mass drug administration programs for lymphatic filariasis elimination

How Albendazole Tablets Work?

In parasite worms, Albendazole works by stopping the production of microtubules. This causes the worms to die by running out of energy and damaging their cells.

This helps reduce pain and inflammation for people with parasitic illnesses.

If you have neurocysticercosis, and the larvae are dying and causing inflammation in the brain, this mixture is very helpful.

Advantages of Albendazole Tablets

Efficacious against a wide landscape of parasitic diseases. Utilized in international deworming initiatives owing to its extensive anthelmintic properties

Applicable for both single-dose regimens and extended therapies. Offered in multiple formulations, including chewable tablets and suspensions, facilitating administration to children

Economical treatment alternative. Generally well-tolerated with negligible adverse effects in the majority of patients

Before Taking This Tablet

  • Medical History Review: Notify your physician of any liver illness, prior bone marrow suppression, or known sensitivities.

  • Liver Function Test: Prolonged usage necessitates monitoring of liver enzymes.

  • Food Interaction: Optimal absorption occurs when taken with food, particularly fatty meals.

  • Avoid grapefruit juice: It may disrupt the metabolism of Albendazole.

Who Should Take Albendazole Tablets?

Albendazole is indicated for:

Patients diagnosed with helminthic infections. Children and adults in endemic regions necessitating deworming

Individuals receiving therapy for neurocysticercosis and hydatid disease. Participants in mass deworming initiatives to avert parasite transmission

Dosage Guidelines for Albendazole Tablets

The dosage of Albendazole is proportional to infection type and patient characteristics:

  • Neurocysticercosis: 400 mg two times daily for 8–30 days

  • Hydatid Disease: 400 mg two times every day for 28 days (repeat cycles may be required)

  • Intestinal Worm Infections: Single 400 mg dose

  • Strongyloidiasis and Taeniasis: 400 mg once daily for 3 days

  • Giardiasis in Children: 400 mg once daily for 5 days

Missed Dose

Take the forgotten dose as quickly as you can. If it is close to the next dose, skip the forgotten dosage and go on with the regular schedule.

Potential Side Effects

  • Headache

  • Dizziness

  • Nausea and vomiting

  • Abdominal pain

  • Elevated liver enzymes

  • Temporary hair loss (reversible)

  • Bone marrow suppression

  • Liver toxicity

  • Severe allergic reactions (rash, swelling, difficulty breathing)

Interactions

Albendazole interacts with certain medications, which may alter its effectiveness:

  • Cimetidine: Increases Albendazole levels in the body

  • Dexamethasone: Enhances Albendazole metabolism

  • Praziquantel: Boosts Albendazole bioavailability

  • Theophylline: Albendazole may affect its metabolism

Route of Administration

Both the tablet and the liquid forms of Albendazole are administered orally. Chewing or swallowing tablets whole with water is recommended based on the formulation.

The suspension, on the other hand, is usually prescribed to children or people who cannot swallow tablets. Albendazole works better with food, especially fatty foods.

They help the body absorb it more easily. The parasite infection type affects the treatment dose and duration.

A person with a systemic infection, like neurocysticercosis or hydatid disease, may require more treatment and higher doses. A doctor should monitor them.

Drug-Drug Interactions Checker List

  • Rifampicin: Reduces Albendazole levels

  • Phenobarbital & Phenytoin: Decrease Albendazole concentration

  • Ketoconazole & Erythromycin: Increase Albendazole concentration

  • Anticoagulants (Warfarin): May increase bleeding risk

Concerns

  • Onset of Action

It starts functioning within a few hours; one can notice peak levels in 2–5 hours.

  • Duration of Effect

It remains effective for 2–3 days after administration.

  • Safe with Alcohol?

No, alcohol increases the risk of liver toxicity. So, it should be completely avoided.

  • Is It Habit-Forming?

No, Albendazole is not addictive. Therefore, a habit will not form.

  • Usage in Pregnancy?

This medication is not suggested in the first trimester, only if benefits are worth taking a chance.

  • Usage While Breastfeeding?

There is very short information on this. Speaking with a doctor before starting this medication while nursing might be wiser.

Precautions, Warnings, and Safety Measures

Long-term use of Albendazole in people with liver disease can increase liver enzymes. This means regular liver function tests are needed.

Albendazole is not to be consumed during the first trimester of expecting. This is because it may cause teratogenic effects.

Women who have chances of pregnancy need to utilize effective contraception during therapy and one month after as well.

Albendazole can cause low white blood cell counts or other blood problems. So, patients with bone marrow issues need careful monitoring.

Alcohol might cause liver damage during therapy, so avoid it. Refrain yourself from taking this medicine if you are allergic to benzimidazoles.

Take Albendazole with food, especially fatty meals. This helps it absorb better and work effectively. Finally, patients should finish treatment to avoid reinfection or resistance.

Storage Conditions

Store between 15-30°C in a cool, arid location

Shield against humidity and direct sunshine

Store out of children’s reach