Valganciclovir Tablets
| Product/Composition:- | Valganciclovir Tablets |
|---|---|
| Strength:- | 450mg |
| Form:- | Tablets |
| Production Capacity | 10 Million Tablets/Month |
| Packaging:- | 1 X 4 Tablets / Box, 1 X 60 Tablets / Box |
| Therapeutic use:- | Antiviral, Anti HIV |
| Package Insert/Leaflet: | Available upon request |
Introduction of Valganciclovir Tablets
Valganciclovir is a strong antiviral medicine. It is mainly used to fight cytomegalovirus (CMV) infections. This is very important for immunocompromised people.
This includes those with HIV/AIDS and organ transplant recipients. This oral prodrug of ganciclovir provides a practical and effective alternative to IV antiviral treatment.
In this way, it is an important part of controlling CMV.
Effective Uses of Valganciclovir Tablets
Valganciclovir is indicated for multiple medical disorders, including:
A serious viral infection of the retina may result in vision impairment, especially in those with AIDS.
Used to prevent CMV infection in patients getting kidney, heart, or kidney-pancreas transplants. The virus can cause serious issues.
Occasionally utilized off-label in neonates with CMV infections to mitigate consequences.
How Do Valganciclovir Tablets Work?
Valganciclovir works by interfering with viral DNA synthesis. This stops the cytomegalovirus (CMV) from replicating and helps achieve its therapeutic effect.
Valganciclovir is converted into ganciclovir by the body after it has been taken. After that, ganciclovir is phosphorylated inside affected cells to turn it into its active triphosphate form.
This active chemical integrates into viral DNA. It stops the DNA from growing and prevents future replication.
Valganciclovir helps control CMV infections by preventing the virus from growing. This helps lessen infection severity and prevent problems.
This is particularly critical for persons with weakened immune systems, such as transplant recipients and HIV/AIDS patients.
Key Medical Benefits
Contraindications of Valganciclovir Tablets
Valganciclovir is contraindicated in persons with:
Significant renal dysfunction or individuals receiving hemodialysis.
Hypersensitivity to valganciclovir, ganciclovir, or any associated chemicals.
Significant hematological abnormalities, including anemia, neutropenia, or thrombocytopenia.
Pregnancy or lactation, as the medication may induce teratogenic effects and reproductive damage.
Individuals intending to conceive, owing to possible enduring impacts on fertility.
Recommended Usage
Dependent on the specific disease and individual patient characteristics. Consistently adhere to the physician’s directives.
Consume with meals to improve absorption. Ingest the pill intact—do not pulverize, masticate, or divide. Adhere to a regular daily schedule for maximum effectiveness.
CMV treatment duration: Generally 21 days. CMV prophylaxis following transplantation: 200 days for kidney transplants and 100 days for other organ transplants.
Side Effects
What special precautions should I follow?
When giving Valganciclovir pills, follow important precautions. This ensures safety and effectiveness. Refrain from use if you are hypersensitive to Valganciclovir or ganciclovir.
Pregnant women should not use this drug because it can cause serious congenital disabilities. Both men and women should utilize efficient contraception while undergoing therapy.
They also need to continue using it for a while after stopping the prescription. Valganciclovir can cause bone marrow suppression.
This leads to lower blood cell counts and raises the risk of infections, bleeding, and anemia. Regular blood tests are necessary to check these effects.
Be careful when you drive or use machines. The medicine might make you feel sleepy or dizzy. Patients with renal impairments necessitate dosage modifications to avert toxicity.
Refrain from close contact with ill patients, as the medication may compromise the immune system. Take the drug exactly as instructed. Please don’t stop taking it without talking to a healthcare expert first.
In Case Of Missed Dose Of Valganciclovir Tablets
If you omit a dosage of Valganciclovir, administer it promptly upon recollection. If your next dose is coming up soon, skip the missed dose.
Then, continue with your regular dosing schedule. Don’t give a second dose if you miss one. This might make side effects more likely.
Most importantly, take your medicine at the same time every day. It helps manage viral infections effectively.
What if I have taken an overdose of Valganciclovir Tablets
An excess of Valganciclovir can be very bad. It could have very bad side effects, like stopping the bone marrow from working.
This can lead to very low blood cell counts and a greater risk of infections. Other risks are bleeding, kidney damage, and neurological problems.
These can cause confusion, seizures, or fainting. If you believe someone has overdosed, get medical attention straight once or contact a poison control center.
In extreme cases, you might need supportive care. This could include hospitalization or blood transfusions.
Safety advice
Regular blood tests should be performed to detect any negative effects.
Hydration is essential—consume ample fluids to facilitate renal function.
Minimize exposure to infections, as your immune system may be weakened.
Refrain from distributing your medication to others.
Special Dietary & Lifestyle Recommendation
Adhere to a balanced diet to enhance immunological function.
Restrict alcohol consumption, as it may exacerbate liver function.
Facilitate adequate rest and stress mitigation to enhance recovery.
Storage Instructions for Valganciclovir Tablets
Maintain at ambient temperature in a desiccated environment.
Avoid exposure to dampness and direct sunlight.
Retain in original packaging to avert deterioration.
Store out of children’s reach.