Sodium Chloride 0.45% & Dextrose 5% Injection
| Product/Composition:- | Sodium Chloride 0.45% & Dextrose 5% Injection |
|---|---|
| Strength:- | 250ml / 500ml / 1000ml |
| Form:- | Injection |
| Production Capacity | 1 Million Injection/Month |
| Therapeutic use:- | Fluid Therapy |
| Package Insert/Leaflet: | Available upon request |
When administered intravenously, these solutions provide a source of water, carbohydrate and electrolytes. Solutions which provide combinations of hypotonic or isotonic concentrations of dextrose and of sodium chloride are suitable for parenteral maintenance or replacement of water and electrolyte requirements with minimal carbohydrate calories.Solutions containing carbohydrate in the form of dextrose restore blood glucose levels and provide calories.
Carbohydrate in the form of dextrose may aid in minimizing liver glycogen depletion and exerts a protein-sparing action. Dextrose injected parenterally undergoes oxidation to carbon dioxide and water. Sodium chloride in water dissociates to provide sodium (Na+) and chloride (Cl¯) ions. Sodium (Na+) is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. Chloride (Cl¯) has an integral role in buffering action when oxygen and carbon dioxide exchange occurs in the red blood cells.
The distribution and excretion of sodium (Na+) and chloride (Cl¯) are largely under the control of the kidney which maintains a balance between intake and output.