Propranolol HCl And Flunarizine Tablets
| Product/Composition:- | Propranolol HCl And Flunarizine Tablets |
|---|---|
| Form:- | Tablet |
| Strength:- | 40mg + 10mg, 20mg + 10mg |
| Production Capacity | 10 Million Tablets / Month |
| Packaging:- | 10X10 Tablets/Box |
| Therapeutic use:- | Anti Anxiety, Anti Depressant, Anti Psychotic, CNS Drugs |
| Package Insert/Leaflet: | Available upon request |
What is Propranolol HCl and Flunarizine Tablets?
Propranolol HCl and Flunarizine Tablets are a combination medication used primarily for the prevention of migraine headaches. Propranolol is a beta-blocker that reduces the frequency and severity of migraines by decreasing the workload on the heart and reducing blood pressure. Flunarizine, a calcium channel blocker, works by stabilizing nerve activity in the brain, thereby preventing the onset of migraines. This combination is effective for patients who experience frequent migraines and need dual therapy to manage their symptoms.
How to Use Propranolol HCl and Flunarizine Tablets
Propranolol HCl and Flunarizine Tablets should be taken as prescribed by your healthcare provider. Typically, the medication is taken once daily, preferably in the evening to minimize the impact of drowsiness, which is a common side effect. It is important to take the tablets consistently to achieve the best results.
How Does Propranolol HCl and Flunarizine Tablets Work?
Propranolol and Flunarizine work together to prevent migraines through different mechanisms:
- Propranolol: By blocking beta-adrenergic receptors, Propranolol reduces the influence of adrenaline on the heart, leading to lower blood pressure and decreased heart rate. This reduction in cardiovascular activity helps prevent the physiological changes that can trigger migraines.
- Flunarizine: This drug blocks calcium channels in the brain, reducing the influx of calcium ions into neurons. This stabilization of nerve activity prevents the constriction of blood vessels in the brain, a common cause of migraine headaches.
How Should I Take Propranolol HCl and Flunarizine Tablets?
Take Propranolol HCl and Flunarizine Tablets as directed by your healthcare provider. The usual starting dose is one tablet daily, taken in the evening. Swallow the tablet whole with a glass of water, and do not crush or chew it. It is important to continue taking the medication even if you feel well, as it is intended to prevent migraines rather than treat them once they occur.
Side Effects
Common side effects of Propranolol HCl and Flunarizine Tablets include:
- Drowsiness
- Weight gain
- Fatigue
- Dry mouth
- Dizziness
- Low blood pressure
- Gastrointestinal disturbances
- Depression
- Bradycardia
- Extrapyramidal symptoms
- Severe hypotension
- Heart block
If you experience any severe side effects, contact your healthcare provider immediately.
Dosage Available
Propranolol HCl and Flunarizine Tablets are available in the following dosages:
- Propranolol 40 mg + Flunarizine 10 mg
- Propranolol 20 mg + Flunarizine 10 mg
The specific dosage will depend on the patient’s condition, response to treatment, and other individual factors.
What Should I Watch for While Using This Medication?
Be vigilant for signs of depression, particularly in patients with a history of mood disorders. Monitor blood pressure regularly, as this medication can lower blood pressure. Alcohol may increase drowsiness and other side effects. Avoid driving or operating machinery if you experience drowsiness or dizziness. Maintain a balanced diet and exercise regularly to manage weight gain. Always inform your healthcare provider about any other medications or supplements you are taking.
Consult your doctor before using this medication if you are pregnant or breastfeeding. Discuss the risks and benefits of long-term use with your healthcare provider. Be aware of symptoms of bradycardia, such as extreme fatigue, dizziness, or fainting. Flunarizine can increase sensitivity to sunlight, so use sunscreen or protective clothing when outdoors.
Missed Dose
If you miss a dose of Propranolol HCl and Flunarizine Tablets, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and resume your normal schedule. Do not double the dose to make up for a missed one.
Overdose
In case of an overdose of Propranolol HCl and Flunarizine Tablets, seek immediate medical attention. Symptoms of overdose may include severe drowsiness, confusion, very slow heart rate, and fainting. Prompt medical intervention is critical to manage the symptoms effectively.
Safety Advice
- Regular Monitoring: Schedule regular appointments with your healthcare provider to monitor your response to the medication.
- Avoid Alcohol: Alcohol may enhance the sedative effects of the medication.
- Caution in the Elderly: Older adults may be more susceptible to side effects, particularly bradycardia and hypotension.
- Pregnancy and Breastfeeding: Use only if clearly needed during pregnancy or breastfeeding.
- Driving and Operating Machinery: Exercise caution when performing activities requiring alertness.
- Dietary Considerations: Watch your diet to manage potential weight gain.
- Hydration: Stay hydrated to help manage dry mouth.
- Sun Protection: Use sunscreen as Flunarizine may increase sun sensitivity.
- Long-term Use: Discuss with your healthcare provider if long-term use is planned.
- Medication Interactions: Always inform your healthcare provider about other medications you are taking.
Brand Names for Propranolol HCl and Flunarizine Tablets
This combination is marketed under various brand names, including:
- Flunolol
- Migrabeta-F
- Migrabeta TR
- Flupro
Market Overview
The market for Propranolol HCl and Flunarizine Tablets has grown steadily over the past five years due to the increasing prevalence of migraine headaches and the effectiveness of this combination therapy in preventing them. The demand for combination therapies like Propranolol and Flunarizine is particularly high among patients who do not respond adequately to single-drug treatments.
The above table illustrates the steady growth in the market for this combination medication, driven by increased awareness and the rising incidence of migraines.
Conclusion
Propranolol HCl and Flunarizine Tablets offer an effective combination therapy for preventing migraines, leveraging the complementary actions of a beta-blocker and a calcium channel blocker. Proper use of this medication can significantly reduce the frequency and severity of migraine attacks, improving the quality of life for patients. The growing market for this combination therapy reflects its importance in migraine management. Patients should consult their healthcare providers to ensure this medication is suitable for their individual needs and to manage any potential side effects effectively.