Naltrexone and Bupropion Tablets

Product/Composition:- Naltrexone and Bupropion Tablets
Form:- Tablets
Packaging:- 10 X 10 Tablets / Box
Strength:- 8mg/90mg
Production Capacity 10 Million Tablets / Month
Therapeutic use:- Analgesic
Package Insert/Leaflet: Available upon request

Bupropion and Naltrexone are a combination drug for weight control. It is for people who are fat or chubby. It is especially for those with weight-related medical problems, like sugar or high blood pressure. This write-up will give you a whole overview of the medicine. It covers its use, side effects, and key precautions.

What are Bupropion and Naltrexone?

Bupropion is an atypical antidepressant. It affects the brain’s neurotransmitters, mainly dopamine and norepinephrine. People often use it to treat sadness and seasonal affective disorder. It can also help with quitting smoking.

Naltrexone is an opioid antagonist. It treats opioid and alcohol addictions. It functions by blocking opioid receptors in the brain. This reduces the pleasure and cravings linked to opioids and alcohol.

These drugs, when combined, work together to aid weight management. They reduce hunger and cravings, especially in obese patients.

Brand Name

The amalgamation of bupropion and Naltrexone is marketed under Contrave. It is extensively utilized as a prescription weight-loss pharmacotherapy sanctioned by the FDA.

Before Taking This Medicine

Before starting bupropion with Naltrexone, give your full medical history to your doctor. The drug may be inappropriate if you possess particular conditions or are using certain medications.

Inform your healthcare provider if you have:

Avoid taking this medication if you are:

How to Use Bupropion and Naltrexone

Take this drug as your healthcare provider instructs. This will maximize its effects and minimize side effects.

The regimen commences with a minimal dose, which is progressively escalated to the full specified amount. This titration approach lowers the possibility of negative effects and allows the body to tolerate the medicine.

Refrain from crushing, chewing, or breaking the tablets. Engaging in this action may elevate the likelihood of adverse repercussions.

 Ingesting the medicine alongside food may mitigate nausea. To prevent sleeplessness, avoid administering the drug late in the evening.

How Does Bupropion and Naltrexone Work?

The amalgamation of bupropion and Naltrexone addresses two pivotal regions in the brain:

It affects dopamine and norepinephrine. They regulate hunger, mood, and energy balance. Bupropion mitigates appetite and cravings by augmenting these neurotransmitters.

Inhibits opioid receptors, diminishing cravings and the pleasurable benefits of eating. It also affects the hypothalamus, the brain’s area for hunger regulation.

Collectively, these benefits facilitate weight reduction by diminishing appetite and regulating food consumption.

How Should I Take Bupropion and Naltrexone?

Follow your doctor’s instructions to the letter when taking bupropion and Naltrexone. To lower the risk of side effects, the medicine is usually started at a smaller dose and slowly raised. Refrain from chewing, crushing, or splitting the tablets; just swallow them whole. Taking the tablets with food is usually best, but not with high-fat meals because they can make you more likely to have seizures. Adhere to the prescribed dosage instructions and refrain from exceeding the authorized amount. Doing so could increase the risk of serious side effects like seizures.

What Should I Avoid While Taking Bupropion and Naltrexone?

What Other Drugs Will Affect Bupropion and Naltrexone?

Elevates the likelihood of seizures and additional adverse effects. High-fat meals May enhance drug absorption and exacerbate adverse effects such as nausea. Opioid Medications May induce abrupt withdrawal symptoms. Avoid using machines until you know the medication’s effects. It may cause dizziness and sleepiness.

What Should I Know About Bupropion and Naltrexone Before Using It?

Bupropion and Naltrexone Dosing Information

The usual way to take medicine is to start with a low amount and slowly increase it over a few weeks to lower the risk of side effects. At first, one tablet is taken every morning for the first week. The second week entails taking two pills daily, one in the morning and one at night. In the third week, the dosage is increased to two tablets taken first thing in the morning and one before bed. And finally, after the fourth week, the daily dose will stay the same: two pills. Do what your doctor says, and don’t take more than the recommended amount.

What Happens If I Miss a Dose?

Unless your next dose is practically approaching, take the missed dose as soon as you remember. Don’t take the missing dosage; instead, resume your usual dosing schedule. Do not take extra pills to make up for the dose you missed.

What Happens If I Overdose?

If someone overdoses, they should get medical help right away. Seizures, confusion, a fast heartbeat, or loss of awareness are some signs. Early intervention is very important to avoid major problems.

Side Effects

What May Interact With This Medication?

Warnings & Precautions

While taking this medicine, keep an eye on your blood pressure daily. Please stay away from drinking because it might make seizures more likely. If you are taking opioid-based drugs or going through opioid detox, do not take this medicine. Tell your doctor if you have had seizures in the past or if you have a disease that makes you more likely to have seizures. Talk to your healthcare provider about any past mental health problems you’ve had, like sadness or suicidal thoughts. Under the supervision of a doctor, slowly stop using sedatives or alcohol before taking the medicine. Pregnant or lactating women should avoid taking this drug since it may damage the newborn. Make sure kids can’t get to the medicine and store it somewhere safe.

What Should I Know About Storage and Disposal of This Medication?

Maintain at ambient temperature, shielded from moisture, heat, and direct sunshine. Adhere to consult local legislation about pharmaceutical disposal or get guidance from a pharmacist. Refrain from flushing the toilet unless directed to do so.

Is There a Special Diet I Need to Follow While on Bupropion-Naltrexone?

Adhere to a diminished-calorie regimen to optimize weight reduction. Emphasize healthy foods, lean proteins, vegetables, and whole grains. Refrain from Consuming High-Fat Meals: They may enhance drug absorption, perhaps resulting in adverse effects.

How Do I Get a Prescription for Bupropion-Naltrexone with Actiza Pharma?

Consult a licensed healthcare professional to evaluate your eligibility for the drug. Actiza Pharma may provide this product. Please inquire about its availability and authorized distributors. While purchasing prescription medications, follow all local laws and regulations.