Amantadine HCl Tablets

Product/Composition:-	Amantadine HCl Tablets
Form:-	Tablet
Strength:-	100mg
Production Capacity	10 Million Tablets / Month
Packaging:-	10 X 10 Tablets / Box
Therapeutic use:-	Anti Anxiety
Package Insert/Leaflet:	Available upon request

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What is Amantadine HCl?

Amantadine Hydrochloride (HCl) is a prescription medication. It is often used for treating Parkinson’s disease, some viral infections, and is occasionally prescribed for drug-induced movement disorders.

It is an antiviral agent and a dopamine agonist. It works in different ways to boost motor function and cut down viral replication.

Amantadine HCl usually comes in tablet form. It provides an effective option for both short-term and long-term treatment.

Uses of Amantadine HCl Tablets

Amantadine HCl tablets are mainly used to manage central nervous system (CNS) issues and viral infections.

The drug helps control symptoms of Parkinson’s disease, a neurodegenerative disorder.

It can also help stop or treat some viral infections, especially those from the influenza A virus.

Indications of Amantadine HCl Tablets

Parkinson’s Disease and Parkinsonism: Amantadine acts as an additional treatment. It helps ease many symptoms of the disease.

Some symptoms are tremors, rigidity, and bradykinesia. These are typical of Parkinson’s disease. It can be given on its own or with other medicines like Levodopa to improve motor function.

Influenza A Virus Infection: Amantadine helps to prevent and treat influenza A virus infections. 

Drug-induced Extrapyramidal Symptoms: In some situations, Amantadine is given to help with side effects such as tremors and rigidity from antipsychotic medications.

Benefits

Amantadine offers several benefits when used for specific medical conditions. For Parkinson’s disease, it can boost motor function, ease rigidity, and help control involuntary movements.

For influenza A, the drug can reduce the duration of symptoms and lower the severity of the infection.

How Does It Work?

Amantadine HCl works by influencing two key pathways. In Parkinson’s disease, it boosts dopamine receptors in the brain. This enhances dopamine activity and improves motor control.

For viral infections, the drug stops the virus from replicating. It does this mainly by blocking the uncoating of the influenza virus. This helps prevent the virus from spreading in the body.

Dosage Guidelines

The dosage of Amantadine HCl tablets can vary and be adjusted. This depends on the patient’s specific medical condition and overall health.

The prescribing doctor must find the right dose. This varies depending on the condition, such as age, weight, and severity. Below are general guidelines:

Amantadine tablets should be taken orally, usually once or twice a day. The tablets must be taken or consumed whole with a proper full glass of water.

It is advisable to always take the medication with the food to reduce potential stomach upset.

The usual starting dose for Parkinson’s disease is 100 mg daily. This dosage may be progressively raised as the patient’s reaction and tolerance allow. For influenza A prevention, a typical dose is 200 mg per day for adults.

Give no amantadine if the patient is allergic to it or any of its components. It is not recommended for individuals with considerable renal or hepatic impairment, or those with a history of seizures.

Can Take With Other Medicines:

Amantadine may be taken alongside other medications, including Levodopa or other Parkinson’s disease treatments, but it is essential to adjust dosages under the supervision of a healthcare provider.

Always inform your healthcare provider about any current medications or supplements being taken to avoid interactions.

Medications to Avoid or Use with Caution

Safety Advice

Before starting Amantadine, check kidney and liver function. If they are not functioning properly, you might have to change the dose.

Regularly checking the mental health of elderly patients is important. Amantadine can cause confusion or hallucinations in some people.

While generally safe when prescribed correctly, Amantadine does come with some concerns. In older patients, the drug can raise the risk of side effects.

They are confusion and hallucinations. Others have dizziness or lightheadedness when standing up. This can increase the risk of falls. Therefore, caution is advised when initiating therapy in older adults.

Pregnancy and Breastfeeding: The safety of amantadine during pregnancy and nursing is unknown.

Amantadine is not recommended during pregnancy unless the potential benefit justifies the potential risk to the fetus. Amantadine may lower the seizure threshold.

This can raise the risk of seizures in those who are vulnerable.

What Else Can I Do to Help My Condition?

You can control Parkinson’s disease or a viral infection by taking Amantadine. Also, consider making lifestyle changes to help.

Physical therapy and exercise can make people with Parkinson’s stronger and more mobile. For influenza A, rest, hydration, and a balanced diet are essential for recovery.

Special Dietary & Lifestyle Recommendations

Diet for Parkinson’s Disease Patients: A balanced diet with antioxidants, fibre, and healthy fats can help manage symptoms. Omega-3 fatty acid supplements and vitamin D are generally recommended for brain health.

Hydration: Hydration is essential when using Amantadine. The use of enough water may decrease side effects such as dry mouth and dizziness.

Influenza Management: If you’re using Amantadine for influenza, remember to rest and stay hydrated. Also, follow any other antiviral treatments your doctor prescribed.

Comparison with Other Treatments

Levodopa is usually the first treatment for Parkinson’s disease. It is appropriate for improving motor function. If you use it for a long time, you may develop problems.

These include motor fluctuations and dyskinesias. Amantadine is often used alongside other treatments. It helps ease symptoms and works well with Levodopa.

This combination improves how Parkinson’s symptoms are managed overall.

Amantadine is an antiviral that treats influenza A. But, it is used less now due to resistance issues. Also, more effective antivirals, like oseltamivir (Tamiflu), are available.

Amantadine still works for some patients who can’t handle other treatments. It also helps with infections from certain strains of influenza.

What Not to Do

Don’t stop Amantadine suddenly without talking to a healthcare provider. This matters for patients with Parkinson’s disease. It might worsen their symptoms.

Do not consume alcohol, as it may worsen side effects such as dizziness or confusion.

Storage Instructions

Store tablets of Amantadine at room temperature. Protect against light and moisture. Keep out of the reach of children.

Do not use the pharmaceutical product beyond the expiration date listed on the packaging.