Sitagliptin Phosphate (Monohydrate/Hydrochloride) API
| Name of Product | Sitagliptin Phosphate Monohydrate/Hydrochloride |
|---|---|
| CAS No | 654671-77-9/486459-71-6 |
| Therapeutic use:- | DPP‑4 inhibitor – oral antidiabetic |
| Grade | IH |
| Form:- | API Powder |
| Status | Commercial |
Product Overview
Sitagliptin Phosphate Monohydrate, or Sitagliptin Hydrochloride, is a DPP-4 enzyme inhibitor used for the treatment of Type 2 Diabetes Mellitus (T2DM).
It helps person with Type 2 Diabetes Mellitus (T2DM) in controlling their blood sugar better.
Sitagliptin functions by preventing DPP-4.
This helps the body’s incretin system, which involves GLP-1 and GIP hormones.
These hormones cause beta cells in the pancreas to produce and secrete more insulin.
They also stop alpha cells from releasing glucagon.
All of this happens based on the amount of glucose that is in the blood.
Therapeutic Applications
Therapeutic class: Antidiabetic agent
It enhances glycemic regulation in people with T2DM.
It is an antidiabetic agent that is generally weight-neutral and has a minimal risk of hypoglycemia.
It is one of the most often prescribed DPP-4 inhibitors across the globe.
It does not cause weight gain, carries a low risk of hypoglycemia, and is well-tolerated by most patients.
Specification Parameters
Packaging & Storage
Sitagliptin Phosphate Monohydrate / Hydrochloride is packed properly in our industry.
This keeps it safe and stable while it is being moved and stored.
Fiber drums are the most common way to get the API. There are two polyethylene bags inside them.
Also, to keep out dirt, light, and moisture, each container is completely sealed.
For storage, the product should be kept in a cool, dry, and air flow type place that is not in harsh sunlight or next to hot temperatures.
To maintain its chemical stability and shelf life, it should be stored at a temperature between 2 and 8 °C.
In these conditions, the material keeps its quality for up to 24 months after it was made.