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Docetaxel (Anhydrous/Trihydrate) API

Name of Product Docetaxel Anhydrous Trihydrate API
CAS No 114977‑28‑5
Therapeutic use:- Taxane antimitotic agent; microtubule inhibitor used in breast, prostate, lung, gastric, head & neck cancers
Grade IP/USP/BP
Form:- API Powder
Status Regular

Product Overview

Docetaxel API is a potent antineoplastic agent that is only partially man-made.

This API is included in the taxane class of chemotherapy treatments.

It is made from the needles of the European yew tree (Taxus baccata) and helps tubulin make stable microtubules.

It also prevents them from breaking down. This stabilization stops cells from dividing normally.

Because of this, it makes cancer cells die by apoptosis, or programmed cell death.

As a first or second treatment for solid tumors, docetaxel is often employed.

It is often used with other solutions that fight cancer. There are two types: anhydrous and trihydrate.

The trihydrate is the one that is employed in clinical preparations.

Therapeutic Applications

Therapeutic class: Anti-cancer

  • Breast Cancer: Early-stage, locally progressed, and metastatic breast cancer (alone or in conjunction with doxorubicin, cyclophosphamide, or trastuzumab).

  • Non-Small Cell Lung Cancer (NSCLC): As both a single treatment and with cisplatin.

  • Prostate Cancer: Commonly administered alongside prednisone for hormone-refractory metastatic prostate cancer.

  • Head and neck cancers: induction chemotherapy treatments focus on squamous cell carcinoma.

    Specification Parameters

    • CAS No. is 114977-28-5

    • C43H53NO14 is the molecular formula for the anhydrous base compound.

    • Molecular Weight is ~807.88 g/mol (without water)

    • Colour is a white to off-white crystalline powder

    • Not very soluble in water; soluble in methanol, ethanol, and DMSO

    • Assay (HPLC) is 99% or more

    • < 0.5% of Related Substances

    Packaging & Storage

    Docetaxel API comes in safe, pharmaceutical-grade packaging to keep it stable and meet international requirements.

    • For secure and proper protection of our solutions, sterile glass vials, aluminium foil or HDPE bottles are utilized for packaging.

    • Clients can get custom packaging if they need it.

    • Keep it dry and between 2°C and 8°C.

    • Protect from light, humidity, and harmful heat.

    • To prevent it from going contaminated, Store in tightly closed containers to avoid contamination.

    • Shelf Life is usually 24 months if stored correctly.

      Why Choose Us

      • Approvals: Facilities that are WHO-GMP and ISO certified make sure that they meet worldwide standards.

      • Quality assurance: Strict quality control using advanced analytical methods like HPLC, GC, and LC-MS.

      • Documentation: Supportive documents from the government, like Drug Master Files (DMFs) and CTD dossiers.

      • Customized Solutions: We can provide the buyer with a customized option for order size and packing. We are flexible like that.

      • Global Reach: We have an established global presence across multiple pharmaceutical markets and they trust us as a partner.

      • On-Time Delivery: A strong supply chain network that guarantees the on-time delivery of the products.