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Diosmin API

Name of Product Diosmin
CAS No 520-27-4
Therapeutic use:- cosmetic
Grade BP/USP
Form:- API Powder
Status Commercial

Product Overview

Diosmin API is a biologically plant-based flavonoid active pharmaceutical ingredient, mainly extracted from citrus sources.

It is a light tan, powder-like material that is used in the development of pharmaceutical formulations.

It helps make medications that benefit blood vessels, maintain normal microcirculation, and facilitate lymphatic flow.

Therapeutic Applications

Diosmin API is used in drugs designed to support venous function and improve circulation.

These products are used to improve vein tone, control swelling, and support lymphatic flow.

The API is frequently added as a single component or complemented by flavonoids that help vascular stability and microcirculation performance to be ​‍​‌‍​‍‌​‍​‌‍​‍‌intensified.

Specification Parameters

The specifications listed here define the quality, identity, and purity needs of Diosmin API for use in pharmaceutical formulations.

  • Molecular Formula: C₂₈H₃₂O₁₅

  • Molecular Weight: 608.54 g/mol

  • CAS Number: 520-27-4

  • Appearance: Tan to off-white crystalline powder

  • Solubility: Practically insoluble in water; slightly soluble in ethanol and methanol.

  • Identification: Confirmed by IR spectrum and chromatographic methods.

  • Assay (Purity): Typically ≥98.5% by HPLC on a dried basis

  • Melting Point: About 274–278 °C

  • Loss on Drying: Not more than 1.0% w/w

  • Heavy Metals: Not more than pharmacopeial limits

  • Related Substances: Individual impurities controlled by HPLC

  • Residual Solvents: Complies with ICH Q3C and USP <467> limits.

  • Microbial Limits: Complies with pharmacopoeial limits for non-sterile APIs (TAMC, TYMC, specified pathogens absent).

  • Elemental Impurities: Controlled as per ICH Q3D guidelines.

Packaging & Storage

Diosmin API comes in layers, packaged in food-grade or pharma-grade plastic bags with two layers.

These bags are then placed inside drums made of fiber or HDPE.

The standard pack sizes are ideal for large-scale handling and transport.

Keep the API in a cool, dry place. Store it away from light, heat, and moisture.

Make sure containers are tightly closed to maintain quality.

Why Choose Us

Actiza Pharmaceutical Pvt. Ltd. is a trusted Indian maker and supplier of Diosmin API.

We provide steady quality and a dependable supply with our top facilities and skilled teams.

Quality Focus

Diosmin API is produced to a very high standard, in line with strict WHO-GMP and ISO guidelines.

Every batch goes through a rigorous testing process and is fully documented.

This keeps API formulations pure, consistent, and safe for use.

Modern Facilities

We have the tools and equipment needed for efficient production.

We use automation, maintain a hygienic environment, and strictly control the process.

These factors reduce human errors, prevent cross-contamination, and maintain API standards.

Strong Integration

We make our own APIs and manage our supply chain well.

This helps us better control sourcing, timelines, and costs.

This backward integration supports dependable availability and smooth coordination for global customers.

Global Support

We serve customers across different locations and allow them to place small orders with us for quick delivery.

Our specialists are ready to help with tech support.

We can also provide the documents you need for regulations. You can reach out to us easily, even across different time zones.