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Betamethasone Sodium Phosphate API

Name of Product Betamethasone Sodium Phosphate
CAS No 151-73-5
Therapeutic use:- Steroids
Grade BP/USP
Form:- API Powder
Status Commercial

Product Overview

Betamethasone sodium phosphate is the sodium phosphate ester of betamethasone, a synthetic fluorinated corticoid.

It is an active pharmacological substance utilized in the creation of systemic and local steroid medications.

However, there are a number of different forms an API can take, depending on the formulation teams needs for the final product.

The betamethasone sodium phosphate form of this API is chosen when precise dosing and a fast, well-controlled response are required.

Therapeutic Applications

It is used solely as an API. Pharmaceutical companies use it to formulate corticosteroid medicines.

  • The final products with this API are usually developed for:

  • Short-term treatment of severe inflammatory conditions

  • Usage in some allergic or immune-related disorders

  • Use when a rapid onset of steroid action is needed.

    At the product level, it is often chosen for:

    • Injectable solutions

    • Eye or ear preparations

    • Other aqueous forms, as permitted by local legislation

      Specification Parameters

      • CAS Number: 151-73-5

      • Chemical Name: Betamethasone 21-phosphate disodium salt

      • Molecular Formula: Câ‚‚â‚‚H₂₈FNaâ‚‚O₈P

      • Molecular Weight: ~516.4 g/mol

      • Appearance: White to almost white crystalline or amorphous powder

      • Solubility: Freely soluble in water, slightly soluble to soluble in ethanol, and practically insoluble in many non-polar solvents. pH (1% aqueous solution): Typically in the slightly acidic to neutral range (spec set by agreement)

      • Purity (HPLC): ≥ 98.0 % (API grade; tighter limits can be agreed)

      • Related Substances: Within agreed limits for individual and total impurities

      • Loss on Drying: ≤ 1.0 % Residue on Ignition / Sulfated Ash: Within agreed limit (often ≤ 0.5 %)

      • Heavy Metals / Elemental Impurities: Within limits based on current guidelines. Identification Tests:

      • IR spectrum matches reference.

      • HPLC retention time matches reference

      • Suitable tests confirmed sodium and phosphate.

        Packaging & Storage

        Betamethasone sodium phosphate is packed in closed, light-protective containers.

        Standard options include HDPE bottles or drums with inner polyethylene or foil bags.

        Each container is clearly labelled with:

        • Product name

        • Batch or lot number

        • Net Weight

        • Manufacturing date

        • Retest or expiry date

          Store the API in a cool, dry place. Avoid direct light, heat, and moisture. 

          When not in use, keep the container securely closed.

          Under the conditions stated below, the product remains within specification throughout the shelf life printed on the label and CoA.

          Why Choose Us

          We supply betamethasone sodium phosphate as a high-quality, consistent API.

          Our production follows strict quality systems and GMP-style controls.

          Every batch is tested for identity, assay, impurities, and key physical properties.

          We can align our specifications with your internal standards where possible.

          Our team can also support you with questions about solubility, processing, and stability.